Where I live, there is one supplier of gasoline and all of the local gas companies buy from this one fuel company, and then add their additives to it later. We have fueling stations that are owned by this *supplier* and it's cheaper per gallon than going to one of the big name stations, but the gas itself doesn't contain any added cleaners. After about 3k-5k miles, there is a noticeable difference in performance and fuel mileage from using this cheaper non-additive containing gas, and a fuel system cleaning is required.
You can see evidence of the increased contaminents by removing the upper intake manifold of an engine and actually looking at how dirty the intake runners are in the heads. There is a brownish buildup all along the runners that isn't as bad when a higher grade fuel is used. Don't get me wrong, there is always going to be a kind of *stain* in the heads, but there's just more of it when comparing the two.
Being around mechanics all my life, and managing a speed shop a few years ago brought this to my attention, and I never bought that particular brand gas again.
Using these types of off-brand fuels isn't that bad if you use a good additive every other tank of fuel, and change your fuel filter regularly, but when you are using all high grade fuels it isn't nearly as necessary, just preventetive.
Something else that's really cool is looking inside an engine before and after an induction service. Absolutely amazing. It goes from looking all brown, dirty, and ugly to like brand new and shiny. At least before and after the BG process, that is, since this is what I am referring to.