I prefer to pour in 1 oz of the Z2 or Z5 first, put in 4 drops of the ZFX, shake well, and then pour in the second ounce of Z2 or Z5, add 4 more drops of the ZFX and shake well. This seems to distribute the ZFX better. Also, don't fill the bottle up to the top, leave some room for the stuff to move around!