Is it safe!

Spray and Gloss is okay only on very light dust. For more substantial dust/dirt, use a QD on steroids like Spray and Wipe or Chemical Guys Speed Wipe.
 
The other gotchas are making sure you have proper soft, plush microfiber to remove your dust or other contaminants because bad mf will also induce swirls. Also, you have to take into account how hard/soft your paint is and whether you can get away with this type of activity. This type of qd dust removal can certainly show more swirls on dark colors than light/metallic colors.
 
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