You don`t have to strip the area with an IPA wipedown, as the abrasives in the polish are going to remove the LSP almost immediately. However it`s not a bad idea to strip the finish anyways because when you abrade the finish (by polishing) and abrade the LSP, some of the LSP is going to get mixed into your polish and pad.
Some products don`t react well contaminated by other products. I always strip my surface with alcohol prior to polishing because I like to set as many variables in my favor as possible.
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