Boon 4376, if you are talking about the foam rods that are used to cram into spaces prior to caulking big gaps (sometimes called 'backer rods'), I think that might be a pretty good idea to get a better seal.
There was a fellow who experimented with small diameter rods like that to get a better seal on his windows. He also found that most of the noise was from the small corner where the window met the door frame, and that a very small bit of the foam stuffed in that corner solved it. But many folks felt that the foam backer rod really helped seal out noise.
$5 foam tube + rubber door seals = less wind noise? - Club Lexus Forums This is the thread. "$5 foam tube + rubber door seals." Go to the third page or so, and there is an improved method suggested by another poster. Also, if you just read the beginning, you will buy 3/8 inch foam, which is probably too large, as folks were cutting it in half length-wise to get the seals to fit back on properly.
Frankly, the seals on my 2003 Civic are like new, but I still think that they should be tighter to limit wind noise better. So I think even with like-new seals, this method could be helpful.